La Mesa Holiday Packages

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Let us bundle your hotels and flights into a tidy little package.

With the extra money you can experience more in La Mesa.

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Wotif boasts some of the most competitive prices anywhere. Better start packing — now's the perfect time for a new adventure.

La Mesa Accommodation

Our database lists 34 accommodations in La Mesa. However, none of them are located directly in the centre. Have a look through your options on Wotif — you're sure to find a great place not too far away.

Searching for somewhere to sleep? No worries — we've got it covered. The Vineyard Hacienda (12685 Campo Rd) and the Holiday Inn Express San Diego South - National City (1645 E Plaza Blvd) both have top reviews and a convenient location.

Car Hire in La Mesa

If you don't have even a minute to lose, the smartest option is to rent a car directly from San Diego International Airport. Economy Rent a car is located near the arrivals area.

There's no need to stress out over hire cars here. Enterprise (8363 Centre Drive, Suite 6H) is our hot tip for this area and is only 2 kilometres from the middle of town.

Holidays to La Mesa

Got a thing for going places you've never visited before? Likewise. But there's no need to get lost in the process. Have a snoop through our guide to La Mesa and you'll be sauntering around like a real local in no time.

The San Diego County neighbourhood of La Mesa sits 16 kilometres from all the excitement of the centre. You'll discover it in the city's east.

If curiosity's your middle name, you'll probably want to learn a few bits of trivia about San Diego County — like how many people call it their home. Well, at last count the population was 1 300 000.

Top La Mesa hotels

Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$528 per night from 30 Nov to 1 Dec
AU$528
30 Nov - 1 Dec
includes taxes & fees
Pendry San Diego: Luxury hotel with free WiFi and an outdoor pool. Located near the airport.
Great room and great staff! They really made our stay with their hospitality and efficiency.

Reviewed on 2 Nov 2025

Opens in a new windowPendry San Diego
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$211 per night from 12 Nov to 13 Nov
AU$211
12 Nov - 13 Nov
includes taxes & fees
Hampton Inn & Suites by Hilton San Diego SeaWorld: Pet-friendly hotel with free breakfast and free WiFi. Located near whale watching.
Good people

Reviewed on 1 Nov 2025

Opens in a new windowHampton Inn & Suites by Hilton San Diego SeaWorld
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$201 per night from 13 Nov to 14 Nov
AU$201
13 Nov - 14 Nov
includes taxes & fees
Hilton San Diego Mission Valley: Business-friendly hotel with free WiFi and an outdoor pool. Located near the airport.
Clean room, good parking, fash check-in & out

Reviewed on 3 Nov 2025

Opens in a new windowHilton San Diego Mission Valley
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.